What Are Polynucleotides?
Polynucleotides are biostimulating injectables derived from purified DNA fragments that stimulate tissue regeneration and skin repair. They are specifically designed to promote fibroblast activity, encouraging the production of collagen, elastin, and other essential components for skin regeneration.
Polynucleotide treatments have been shown to:
- Improve skin elasticity and hydration.
- Stimulate tissue repair and cell renewal.
- Reduce fine lines and wrinkles.
- Support skin healing after other aesthetic treatments.
What Is Profhilo?
Profhilo is a next-generation skin remodeling treatment composed of highly concentrated hyaluronic acid (HA). Unlike traditional skin boosters, Profhilo uses patented NAHYCO® hybrid technology, allowing it to deliver both hydration and biostimulation effects.
Profhilo is injected into specific points (Bio Aesthetic Points) on the face and spreads evenly to:
- Improve skin hydration.
- Enhance skin firmness and elasticity.
- Smooth fine lines and wrinkles.
- Stimulate collagen and elastin production.
Key Differences Between Polynucleotides and Profhilo
Active Ingredient: Polynucleotides are DNA-based biostimulants, while Profhilo is a hyaluronic acid skin booster.
Primary Action: Polynucleotides stimulate skin repair and regeneration, while Profhilo provides intensive deep hydration and skin remodelling.
Collagen Stimulation: Polynucleotides have a stronger effect on collagen production due to their action on cells responsible for regeneration.
Hydration: Profhilo is more effective for patients focusing on skin hydration and a brighter complexion.
Ideal For: Polynucleotides are suited for improving elasticity, healing damaged skin, and softening wrinkles. Profhilo is preferred for hydrating effects and achieving a glowing, youthful skin.
Benefits of Polynucleotides
- Boosts collagen and elastin production.
- Strengthens skin tissue.
- Supports healing of damaged skin.
- Improves elasticity and firmness.
- Reduces fine lines, wrinkles, and signs of ageing.
- Particularly effective for delicate areas like under the eyes.
Benefits of Profhilo
- Provides deep hydration and enhances skin texture.
- Increases skin elasticity.
- Gives a natural, youthful appearance.
- Smooths fine lines and rejuvenates mature skin.
- Achieves a healthy glow with minimal downtime.
Which Treatment Is Best for Your Skin Type?
- Polynucleotides are recommended if your main goal is regeneration, healing, and firming, particularly for mature skin or damaged skin.
- Profhilo is ideal if you're looking for an overall skin boost, enhanced hydration, and a radiant complexion.
- For some, combining both treatments may be the most effective approach to achieve long-lasting results.
How Long Do the Results Last?
- Polynucleotides typically offer results lasting 6–9 months, depending on skin type and maintenance.
- Profhilo provides results for around 6 months, with most patients opting for a treatment option every 6 months to maintain results.
Consistency is key to maximising the benefits of skin boosters.
Side Effects and Risks of Polynucleotides vs Profhilo
Both treatments are safe when performed by expert practitioners but may cause temporary effects such as:
- Mild swelling, redness, or bruising.
- Tenderness at the injection site.
- Rare allergic reactions.
With proper technique, the risk of complications is very low.
Which Treatment Is Right for You?
Choosing the right type of skin booster depends on:
- Your specific skin goals.
- Whether you seek hydration, regeneration, or both.
- Your skin's current condition and sensitivity.
At Oracle Clinics, our RN Ness Griffiths will assess your skin during a consultation and recommend a tailored treatment plan to achieve healthier, more youthful-looking skin.
Guiding you through the next stage
Both Polynucleotides and Profhilo are highly effective popular skin treatments, each offering unique benefits. Whether you’re aiming for skin regeneration, a youthful appearance, or deep hydration, both treatments deliver noticeable improvements and a radiant complexion.
For personalised advice, book a consultation with Oracle Clinics and discover which option is best for you.
